Scientists have examined the genetic history of a large group of cheetahs and have found that
there was a significant decrease in the genetic diversity of the cheetah species about 10,000 years
ago. Scientists found that, even in unrelated groups of cheetahs, individual cheetahs had 99% of
the same alleles. By comparison, in a genetically diverse population, even closely related
individuals contain only 80% of the same alleles. Genetic diversity is important to the survival of a
species, and scientists worry that a disease that cheetahs are not resistant to could decimate the
population.
Major histocompatibility complex (MC) genes are used by the body to identify self from non-self
and direct the immune system to attack non-self particles. Invading bacteria and viruses do not
contain the same MHC genes and therefore are attacked by the immune system. Within a
population, a high diversity of MHC genes protects the population from attack by disease. In a
highly diverse population, it is likely that at least some individuals will contain an allele that
identifies a new disease as non-self and can direct the immune system to destroy it.
In 1985, research by Stephen O'Brien reported that skin grafts from cheetahs in a zoo in Oregon
were accepted by cheetahs in Africa. Skin grafts, like other organ donations, must be between
Individuals that have the same MHC factors. If any of the genetic factors are different, then the
immune system of the individual receiving the organ will identify the organ as non-self and the
body will attack the donated organ as if it were a foreign organism such as a virus or bacterium.
The conclusion from
O'Brien's research was that cheetah MHC genes are as alike as those of identical twins.
More recent research by Simone Sommer took a much more comprehensive approach to
examining the genes of a large sample of wild cheetahs. Sommer's research determined how
many alleles are present on two different types of MHC genes in approximately 150 cheetahs.
Sommer was able to show that the variation in some MHC genes was higher than previously
thought. The variation in MHC genes in cheetahs is still smaller than that for other big cat species
but appears to be sufficient to allow the populations to identify a wide variety of foreign particles.
Why is the conclusion about gene variation among cheetahs from Sommer's research more valid than the conclusion from O'Brien's research?
- A. Sommer's research was conducted more recently than O'Brien's
- B. Sommer's research used a different population of cheetahs than O'Brien's
- C. Sommer's conclusion is about disease response, while O'Brien's is about skin grafts.
- D. Sommer's conclusion is based on examining the genes, while O'Brien's conclusion is based on acceptance of a skin graft.
Correct Answer & Rationale
Correct Answer: D
Sommer's conclusion is more valid as it directly examines gene variation, providing a clearer understanding of genetic factors influencing traits. This direct analysis allows for more reliable insights into gene functionality. In contrast, O'Brien's research focuses on skin graft acceptance, which, while informative, does not provide the same depth of genetic examination. Option A is incorrect as recency does not inherently validate research findings. Option B is misleading; differing populations may affect findings but do not necessarily validate one conclusion over another. Option C misrepresents the focus of the studies; both are relevant but differ in application rather than validity.
Sommer's conclusion is more valid as it directly examines gene variation, providing a clearer understanding of genetic factors influencing traits. This direct analysis allows for more reliable insights into gene functionality. In contrast, O'Brien's research focuses on skin graft acceptance, which, while informative, does not provide the same depth of genetic examination. Option A is incorrect as recency does not inherently validate research findings. Option B is misleading; differing populations may affect findings but do not necessarily validate one conclusion over another. Option C misrepresents the focus of the studies; both are relevant but differ in application rather than validity.
Other Related Questions
The Punnett square below shows a cross between a male long-haired cat with white fur and a female short-haired cat with colored fur... what is the most likely number of long-haired kittens with colored fur?
- A. 10
- B. 20
- C. 30
- D. 60
Correct Answer & Rationale
Correct Answer: A
In a Punnett square, the genetic traits of the parents are combined to predict offspring traits. Long hair (L) is dominant over short hair (l), and colored fur (C) is dominant over white fur (c). The male cat is homozygous for long hair and white fur (LLcc), while the female is homozygous for short hair and colored fur (llCC). The resulting genotype for the kittens will be LlCc, indicating they will all have long hair and colored fur. Option A (10) reflects the expected number of long-haired, colored kittens based on the given parental genotypes. Options B (20), C (30), and D (60) suggest higher numbers that do not align with the predicted offspring ratio from the cross, thus they are incorrect.
In a Punnett square, the genetic traits of the parents are combined to predict offspring traits. Long hair (L) is dominant over short hair (l), and colored fur (C) is dominant over white fur (c). The male cat is homozygous for long hair and white fur (LLcc), while the female is homozygous for short hair and colored fur (llCC). The resulting genotype for the kittens will be LlCc, indicating they will all have long hair and colored fur. Option A (10) reflects the expected number of long-haired, colored kittens based on the given parental genotypes. Options B (20), C (30), and D (60) suggest higher numbers that do not align with the predicted offspring ratio from the cross, thus they are incorrect.
Scientists can indirectly observe temperatures and insolation (the Intensity or direct solar radiation) in the distant past by measuring oxygen isotope ratios in ice cores collected from polar ice. The graph presents data for the period from what ta200.000 years ago. What time period in the graph shows the greatest correlation between Milankovitch cycles and climate?
- A. 140,000-160,000 years ago
- B. 120,000-140,000 years ago
- C. 100,000-120,000 years ago
- D. 160,000-180,000 years ago
Correct Answer & Rationale
Correct Answer: C
The time period from 100,000 to 120,000 years ago exhibits the greatest correlation between Milankovitch cycles and climate, as evidenced by significant fluctuations in temperature and insolation reflected in the oxygen isotope ratios. This interval aligns closely with the timing of glacial and interglacial periods influenced by Earth's orbital changes. Options A and B show notable climate changes, but they do not align as strongly with Milankovitch cycles, indicating less correlation. Option D, while part of the broader glacial cycle, reveals less pronounced temperature shifts, making it less relevant to the question of correlation.
The time period from 100,000 to 120,000 years ago exhibits the greatest correlation between Milankovitch cycles and climate, as evidenced by significant fluctuations in temperature and insolation reflected in the oxygen isotope ratios. This interval aligns closely with the timing of glacial and interglacial periods influenced by Earth's orbital changes. Options A and B show notable climate changes, but they do not align as strongly with Milankovitch cycles, indicating less correlation. Option D, while part of the broader glacial cycle, reveals less pronounced temperature shifts, making it less relevant to the question of correlation.
The graph shows results from a study that sought to determine average exposure to triclosan in the U.S. population. Which statement is supported by the results in the graph?
- A. Triclosan concentration does not vary significantly among different age groups.
- B. Increased levels of triclosan in urine are related to increased age.
- C. Triclosan concentration in urine is highest in the 30- to 39-year-old age group.
- D. People aged 20-29 likely use more products containing triclosan.
Correct Answer & Rationale
Correct Answer: C
The data indicates that the highest triclosan concentration in urine occurs in the 30- to 39-year-old age group, supporting option C. This finding highlights a specific peak in exposure among this demographic. Option A is incorrect as the graph likely shows variation in triclosan levels across age groups. Option B misinterprets the data; the graph does not suggest that triclosan levels increase with age. Option D assumes usage patterns without evidence from the graph, which focuses on urinary concentration rather than product usage.
The data indicates that the highest triclosan concentration in urine occurs in the 30- to 39-year-old age group, supporting option C. This finding highlights a specific peak in exposure among this demographic. Option A is incorrect as the graph likely shows variation in triclosan levels across age groups. Option B misinterprets the data; the graph does not suggest that triclosan levels increase with age. Option D assumes usage patterns without evidence from the graph, which focuses on urinary concentration rather than product usage.
What statement describes one or more needed changes to this experiment that would allow the experimenter to draw a valid conclusion?
- A. Salt water should have been used to make the ice cubes for the cup of salt water.
- B. The time for ice cubes to melt should have been measured in minutes.
- C. At the beginning, both cups should have contained the same mass of water at the same temperature.
- D. The energy released should have been measured, not calculated.
Correct Answer & Rationale
Correct Answer: C
Option C highlights the necessity for both cups to start with the same mass of water at the same temperature to ensure a fair comparison. This control eliminates variables that could skew results, allowing for a valid conclusion about the melting rates of ice cubes in different solutions. Option A is incorrect because using salt water to make ice cubes would not provide relevant data on how the ice behaves in fresh versus salt water. Option B is not a change that affects the experimental validity; measuring time in minutes is appropriate, but the key is ensuring conditions are equal. Option D suggests a measurement method change, but calculating energy based on temperature changes is acceptable in this context.
Option C highlights the necessity for both cups to start with the same mass of water at the same temperature to ensure a fair comparison. This control eliminates variables that could skew results, allowing for a valid conclusion about the melting rates of ice cubes in different solutions. Option A is incorrect because using salt water to make ice cubes would not provide relevant data on how the ice behaves in fresh versus salt water. Option B is not a change that affects the experimental validity; measuring time in minutes is appropriate, but the key is ensuring conditions are equal. Option D suggests a measurement method change, but calculating energy based on temperature changes is acceptable in this context.